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Year : 2020  |  Volume : 3  |  Issue : 2  |  Page : 75-77

Degree of proteinuria as a predictor of severity in diffuse proliferative glomerulonephritis: An experience from Sri Lanka

1 Department of Pathology, Faculty of Medicine, University of Peradeniya, Kandy, Sri Lanka
2 Department of Pediatrics, Faculty of Medicine, University of Peradeniya, Kandy, Sri Lanka
3 Department of Emergency Medicine, Teaching Hospital Peradeniya, Peradeniya, Sri Lanka

Correspondence Address:
Kanchana Sanjeewani Liyanaarachchi
Department of Pathology, Royal Surrey County Hospital, Guilford, England
Sri Lanka
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/2589-9309.305917

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Acute glomerulonephritis (AGN) or infection-related glomerulonephritis (IRGN) is the leading cause of acute nephritic syndrome in developing countries. We examined for differences in histopathological pattern and severity of injury in 48 patients with IRGN, categorized by the degree of proteinuria as nonnephrotic and nephrotic range, and compared the levels of serum albumin and degree of tubular injury between the two groups. Patients with nephrotic range proteinuria had a more severe glomerular and tubular injury and had double contours more often than patients with nonnephrotic range proteinuria.

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